Unit Outline
CXA651
Clinical Chemistry 1
Semester 2, 2024
Jeff Beckett
School of Health Sciences
College of Health and Medicine
CRICOS Provider Code: 00586B

Unit Coordinator
Jeff Beckett
Email: Jeffrey.Beckett@utas.edu.au
 

What is the Unit About?
Unit Description
The unit CXA651, Clinical Chemistry 1 will provide you with a thorough knowledge of: quality assurance, including sources of error; use and establishment of reference ranges; collection, preservation, transportation and storage of specimens for analysis and the preparation of laboratory method manuals. The laboratory investigations of renal function, water, electrolyte and acid base balance, and hypothalamic, pituitary and fertility hormones are also studied. This unit is co-taught with a related unit to students in the Bachelor of Laboratory Medicine, and although you will be provided with similar knowledge and laboratory skills as these students, you will also undertake additional learning activities and assessment. This is necessary for you to develop and demonstrate the higher level investigatory and communication skills to satisfy the Australian Qualification Framework level 9 requirements of a Master’s degree.
Intended Learning Outcomes
As per the Assessment and Results Policy 1.3, your results will reflect your achievement against specified learning outcomes.
On completion of this unit, you will be able to:
1.
Demonstrate a detailed knowledge of clinical chemistry principles.
2.
Communicate in a scientific manner using discipline specific terminology related to clinical chemistry.
3.
Perform laboratory techniques and calculations competently and accurately
4.
Critically assess laboratory results and evaluate the clinical relevance of case studies to peers.
5.
Apply technical skills to obtain reliable results in the laboratory
Alterations as a result of student feedback
No alterations have been made as a result of student feedback.
 
 

Teaching arrangements
ATTENDANCE MODE
TEACHING TYPE
LEARNING ACTIVITY
CONTACT HOURS
FREQUENCY
On Campus
Independent Learning
Online pre-recorded lecture content.
2
Weekly
Tutorial
Face to face tutorial and pre-lab presentations.
1
Weekly
Practical
Face to face practical for development and application of technical skills in context of weekly module concepts and content.
3
Weekly
Tutorial
Master’s only tutorials
1
Study Period 2 times
Attendance / engagement expectations
If your unit is offered On campus, it is expected that you will attend all on-campus and onsite learning activities. This is to support your own learning and the development of a learning community within the unit. If you are unable to attend regularly, please discuss the situation with your course coordinator and/or our UConnect support team.

If your unit is offered Online or includes online activities, it is expected you will engage in all those activities as indicated in the Unit Outline or MyLO, including any self-directed learning.

If you miss a learning activity for a legitimate reason (e.g., illness, carer responsibilities) teaching staff will attempt to provide alternative activities (e.g., make up readings) where it is possible.
 
 
 
 

How will I be Assessed?
 
For more detailed assessment information please see MyLO.
Assessment schedule
ASSESSMENT TASK #
ASSESSMENT TASK NAME
DATE DUE
WEIGHT
LINKS TO INTENDED LEARNING OUTCOMES
Assessment Task 1:
Laboratory Report
See the MyLO site for the due date
15 %
LO1, LO2, LO4
Assessment Task 2:
Written Case Study
See the MyLO site for the due date
15 %
LO1, LO2, LO4
Assessment Task 3:
Skills and Competencies Test
Week 4
0 %
LO3, LO5
Assessment Task 4:
Method Protocol
Week 5
10 %
LO1, LO2
Assessment Task 5:
Quiz
Week 7
10 %
LO1, LO2, LO3, LO4
Assessment Task 6:
Practical Exam
Exam Period
25 %
LO1, LO2, LO3, LO4, LO5
Assessment Task 7:
Examination
Exam Period
25 %
LO1, LO2, LO3, LO4
 
Assessment details
Assessment Task 1: Laboratory Report
Task Description:
Laboratory Report.
During the semester, you will complete two written laboratory reports (one formative and one summative) based on practical sessions. Reports must be written to conform to the provided format.
Task Length:
1500 words
Due Date:
See the MyLO site for the due date
Weight:
15 %
 
CRITERION #
CRITERION
MEASURES INTENDED
LEARNING OUTCOME(S)
1
Explain relevant principles of clinical chemistry
LO1, LO2
2
Method describes laboratory activities undertaken
LO2
3
Analyse and interpret data collected in the laboratory to explain clinical chemistry principles
LO1, LO2, LO4
4
Critically assess laboratory results and use evidence to explain clinical relevance and draw valid conclusions
LO1, LO2, LO4
5
Critically evaluate experiment to suggest improvements
LO1, LO4
6
Report conforms to scientific writing requirements for a laboratory report and uses discipline specific terminology and refers to literature
LO2
 
Assessment Task 2: Written Case Study
 

Task Description:
Written Case Study.
You will be given a Case Study covering Water Balance, Renal Function, Electrolyte Balance and Acid Base Balance. You are required to research the case study, performing any relevant additional calculations, and describe the pathophysiology.
Task Length:
1200 words
Due Date:
See the MyLO site for the due date
Weight:
15 %
 
CRITERION #
CRITERION
MEASURES INTENDED
LEARNING OUTCOME(S)
1
Communicate ideas and information using clinical chemistry principles to explain the case study
LO1, LO2, LO4
2
Use laboratory results to explain the case study clinical relevance and disease process
LO1, LO2, LO4
3
Present the case using discipline specific terminology
LO2
 
Assessment Task 3: Skills and Competencies Test
Task Description:
Skills and Competencies Test.
This skills and competencies test is a hurdle task to determine that you have the required skills on which to build further laboratory skills. The session will examine basic pipetting.
Task Length:
3 hours
Due Date:
Week 4
Weight:
0 %
 
CRITERION #
CRITERION
MEASURES INTENDED
LEARNING OUTCOME(S)
1
Perform laboratory and analytical techniques
LO3, LO5
 
Assessment Task 4: Method Protocol
Task Description:
Method Protocol.
You will prepare a method protocol on the spectrophotometric assay of an analyte of your choice based on current NATA requirements. Protocols must be written to conform with the provided format.
Task Length:
1000 words
Due Date:
Week 5
Weight:
10 %
 
CRITERION #
CRITERION
MEASURES INTENDED
LEARNING OUTCOME(S)
1
Chosen analyte and method are appropriate for a spectrophotometric assay.
LO1
2
Method conforms to NPAAC guidelines
LO1, LO2
3
Laboratory specific information and QC requirements are described in method
LO1, LO2
4
Research and relevant information are integrated into the method
LO2
5
Method is written in a concise and structured manner using discipline specific terminology
LO2
 

 
Assessment Task 5: Quiz
Task Description:
Quiz.
A 50 minute quiz comprising calculations, short answers and case studies.
Task Length:
50 minutes
Due Date:
Week 7
Weight:
10 %
 
CRITERION #
CRITERION
MEASURES INTENDED
LEARNING OUTCOME(S)
1
Perform clinical chemistry calculations
LO1, LO3
2
Use clinical chemistry principles to explain diseases
LO1, LO2, LO4
3
Critically assess laboratory results
LO4
4
Use discipline specific terminology
LO2
 
Assessment Task 6: Practical Exam
Task Description:
A three hour practical exam will be conducted during the formal examination period. The exam will involve the application of techniques studied during the semester, demonstration of laboratory competency and the interpretation of results obtained. The exam will be marked on the accuracy of laboratory results and the completeness of result interpretation and questions. The practical examination is a hurdle task that students are required to pass to be eligible for a pass grade or better in this unit. This task assesses competencies that contribute to core claims of competency for medical scientists.
Task Length:
3 hours
Due Date:
Exam Period
Weight:
25 %
 
CRITERION #
CRITERION
MEASURES INTENDED
LEARNING OUTCOME(S)
1
Demonstrate knowledge of clinical chemistry principles
LO1
2
Use technical skills to obtain results in the laboratory
LO1, LO5
3
Perform laboratory techniques and calculations
LO2, LO3, LO5
4
Assess laboratory results and evaluate the clinical relevance
LO1, LO2, LO4
 
Assessment Task 7: Examination
Task Description:
This is a closed book paper-based exam, where you will be required to demonstrate your individual ability to communicate and apply theoretical and practical knowledge. You may take one A4 double sided or two A4 single sided pages of typed notes into the exam.
Task Length:
3 hours
Due Date:
Exam Period
Weight:
25 %
 

 
CRITERION #
CRITERION
MEASURES INTENDED
LEARNING OUTCOME(S)
1
Demonstrate knowledge of clinical chemistry principles
LO1, LO3
2
Critically assess laboratory results and evaluate the clinical relevance
LO2, LO4
3
Complete clinical chemistry calculations
LO3
4
Communicate in a scientific manner using discipline specific terminology.
LO2
 
 
 

How your final result is determined
To pass this unit, you need to demonstrate your attainment of each of the Intended Learning Outcomes, achieve a final unit grade of 50% or greater, and pass any hurdle tasks.
Submission of assignments
Where practicable, assignments should be submitted to an assignment submission folder in MYLO. You must submit assignments by the due date or receive a penalty (unless an extension of time has been approved by the Unit Coordinator). Students submitting any assignment in hard copy, or because of a practicum finalisation, must attach a student cover sheet and signed declaration for the submission to be accepted for marking.
Academic integrity
Academic integrity is about acting responsibly, honestly, ethically, and collegially when using, producing, and communicating information with other students and staff members.

In written work, you must correctly reference the work of others to maintain academic integrity. To find out the referencing style for this unit, see the assessment information in the MyLO site, or contact your teaching staff. For more detail about Academic Integrity, see
Important Guidelines & Support.
Requests for extensions
If you are unable to submit an assessment task by the due date, you should apply for an extension.
 
A request for an extension should first be discussed with your Unit Coordinator or teaching support team where possible. A request for an extension must be submitted by the assessment due date, except where you can provide evidence it was not possible to do so. Typically, an application for an extension will be supported by documentary evidence: however, where it is not possible for you to provide evidence please contact your Unit Coordinator.
 
The Unit Coordinator must notify you of the outcome of an extension request within 3 working days of receiving the request.
Late penalties
Assignments submitted after the deadline will receive a late penalty of 5% of the original available mark for each calendar day (or part day) that the assignment is late. Late submissions will not be accepted more than 10 calendar days after the due date, or after assignments have been returned to other students on a scheduled date, whichever occurs first. Further information on Late Penalties can be found on the Assessments and Results Procedure.
Review of results and appeals
You are entitled to ask for a review of the marking and grading of your assessment task if there is an irregularity in the marking standards or an error in the process for determining the outcome of an assessment. Details on how to request a review of a mark for an assignment are outlined in the Review and Appeal of Academic Decisions Procedure.
 
 

 
 

Required Resources
Required reading materials
Tietz fundamentals of clinical chemistry and molecular diagnostics; 8th Ed; Elsevier
Nader Rifai; Andrea R. Horvath; C. Wittwer; Norbert W. Tietz 2019
 
Recommended reading materials
 
 
Other required resources