Unit Outline
CSA414
Clinical Pharmacokinetics 4
Semester 1, 2024
Daniel Hoyle
School of Pharmacy and Pharmacology
College of Health and Medicine
CRICOS Provider Code: 00586B

Unit Coordinator
Daniel Hoyle
Email: Daniel.Hoyle@utas.edu.au
 

What is the Unit About?
Unit Description
A study of the clinical pharmacokinetics of individual drugs and groups of drugs, sources of inter-patient variability in pharmacokinetics and the application of pharmacokinetics in practice. As with Clinical Pharmacokinetics 3, particular emphasis is placed on the role of the pharmacist in improving the use of drugs through the practical application of pharmacokinetics and therapeutic drug monitoring. There is extensive use of clinically oriented problems and cases. Topics include therapeutic drug monitoring; drug interactions; an overview of sources of inter-patient variability in pharmacokinetics (eg extremes of age, renal or hepatic disease, pharmacogenomics); clinical case studies and pharmacokinetics of specific drugs. Unit objective: to develop the ability to contribute to improved drug use through the appropriate use of pharmacokinetic techniques and therapeutic drug monitoring.
Intended Learning Outcomes
As per the Assessment and Results Policy 1.3, your results will reflect your achievement against specified learning outcomes.
On completion of this unit, you will be able to:
1.
Resolve clinical problems and optimise the quality use of medicines by applying pharmaceutical and pharmacokinetic principles.
2.
Perform advanced pharmaceutical and pharmacokinetic calculations used in pharmacy and clinical practice.
3.
Develop and deliver health and medicines education and/or advice for a range of audiences.
Requisites
REQUISITE TYPE
REQUISITES
Pre-requisite
CSA311 AND All Year 2 BPharm Units
Alterations as a result of student feedback
There have been a number of changes to the assessment this year in line with changes to the unit and as a result of student feedback. 
 
 

Teaching arrangements
ATTENDANCE MODE
TEACHING TYPE
LEARNING ACTIVITY
CONTACT HOURS
FREQUENCY
On Campus
Workshop
2hr workshop weekly
2
Weekly
Independent Learning
Online learning resources (equivalent to 2 hours of activity per week)
2
Weekly
Attendance / engagement expectations
If your unit is offered On campus, it is expected that you will attend all on-campus and onsite learning activities. This is to support your own learning and the development of a learning community within the unit. If you are unable to attend regularly, please discuss the situation with your course coordinator and/or our UConnect support team.

If your unit is offered Online, it is expected you will engage in all those activities as indicated in the Unit Outline, including any self-directed learning.

If you miss a learning activity for a legitimate reason (e.g., illness, carer responsibilities) teaching staff will attempt to provide alternative activities (e.g., make up readings) where it is possible.
 
 
 
 

How will I be Assessed?
 
For more detailed assessment information please see MyLO.
Assessment schedule
ASSESSMENT TASK #
ASSESSMENT TASK NAME
DATE DUE
WEIGHT
LINKS TO INTENDED LEARNING OUTCOMES
Assessment Task 1:
In-class quizzes
Week 2
10 %
LO1, LO2
Assessment Task 2:
Portfolio
Week 4
30 %
LO1, LO3
Assessment Task 3:
Mid-semester test
Week 8
20 %
LO1, LO2, LO3
Assessment Task 4:
Exam
Week 13
40 %
LO1, LO2, LO3
 
Assessment details
    
Assessment Task 1: In-class quizzes
Task Description:
You will undertake regular in-class tests during the timetabled workshops which will contain multiple-choice questions (MCQs) or short-answer questions (SAQs).

Due Dates: Weeks 2- 7, 9- 12

Task Length:
10 minutes
Due Date:
Week 2
Weight:
10 %
 
CRITERION #
CRITERION
MEASURES INTENDED
LEARNING OUTCOME(S)
1
Apply pharmaceutical and pharmacokinetic principles to resolve clinical problems and improve the quality use of medicines.
LO1
2
Perform and interpret advanced pharmaceutical and pharmacokinetic calculations used in pharmacy and clinical practice.
LO2
 
Assessment Task 2: Portfolio
Task Description:
You will be required to build an individual portfolio of short videos that demonstrates the communication of pharmacokinetic principles to a variety of audiences utilising audiovisual media.

Due Dates:
Video 1: Week 4
Video 2: Week 7
Video 3: Week 11

Task Length:
Variable
Due Date:
Week 4
Weight:
30 %
 
 

CRITERION #
CRITERION
MEASURES INTENDED
LEARNING OUTCOME(S)
1
Communicate pharmacokinetic principles with depth, clarity and language tailored to the target audience and media type.
LO3
2
Discuss pharmacokinetic principles and their implications when resolving clinical problems or improving the quality use of medicines.
LO1
 
Assessment Task 3: Mid-semester test
Task Description:
You will undertake a written mid-semester test which will include multi-choice questions (MCQs) and/or short-answer questions (SAQs) relating to the application of pharmacokinetic principles and your ability to perform pharmacokinetic and pharmaceutical calculations.

Task Length:
50 minutes
Due Date:
Week 8
Weight:
20 %
 
CRITERION #
CRITERION
MEASURES INTENDED
LEARNING OUTCOME(S)
1
Apply pharmaceutical and pharmacokinetic principles to resolve clinical problems and improve the quality use of medicines.
LO1
2
Perform and interpret advanced pharmaceutical and pharmacokinetic calculations used in pharmacy and clinical practice.
LO2
3
Communicate pharmacokinetic principles with depth, clarity and language tailored to the target audience.
LO3
 
Assessment Task 4: Exam
Task Description:
You will undertake a 2-hour written exam under formal exam conditions which will include a mix of theory and calculations.

Task Length:
2 hours
Due Date:
Week 13
Weight:
40 %
 
CRITERION #
CRITERION
MEASURES INTENDED
LEARNING OUTCOME(S)
1
Apply pharmaceutical and pharmacokinetic principles to resolve clinical problems and improve the quality use of medicines.
LO1
2
Perform and interpret advanced pharmaceutical and pharmacokinetic calculations used in pharmacy and clinical practice
LO2
3
Communicate pharmacokinetic principles with depth, clarity and language tailored to the target audience.
LO3
 
 
 

How your final result is determined
To pass this unit, you need to demonstrate your attainment of each of the Intended Learning Outcomes and achieve a final unit grade of 50% or greater.
 
Submission of assignments
Where practicable, assignments should be submitted to an assignment submission folder in MYLO. You must submit assignments by the due date or receive a penalty (unless an extension of time has been approved by the Unit Coordinator). Students submitting any assignment in hard copy, or because of a practicum finalisation, must attach a student cover sheet and signed declaration for the submission to be accepted for marking.
 
Requests for extensions
If you are unable to submit an assessment task by the due date, you should apply for an extension.
 
A request for an extension should first be discussed with your Unit Coordinator or teaching support team where possible. A request for an extension must be submitted by the assessment due date, except where you can provide evidence it was not possible to do so. Typically, an application for an extension will be supported by documentary evidence: however, where it is not possible for you to provide evidence please contact your Unit Coordinator.
 
The Unit Coordinator must notify you of the outcome of an extension request within 3 working days of receiving the request.
Late penalties
Assignments submitted after the deadline will receive a late penalty of 5% of the original available mark for each calendar day (or part day) that the assignment is late. Late submissions will not be accepted more than 10 calendar days after the due date, or after assignments have been returned to other students on a scheduled date, whichever occurs first. Further information on Late Penalties can be found on the Assessments and Results Procedure.
 
Review of results and appeals
You are entitled to ask for a review of the marking and grading of your assessment task if there is an irregularity in the marking standards or an error in the process for determining the outcome of an assessment. Details on how to request a review of a mark for an assignment are outlined in the Review and Appeal of Academic Decisions Procedure.
 
 
 

Required Resources
Required reading materials
No required reading materials.
 
Recommended reading materials
Birkett DJ. Pharmacokinetics Made Easy, McGraw Hill: 2009.
Shargel L, Wu-Pong S, Yu ABC: Applied Biopharmaceutics and Pharmacokinetics, 7th Edition, McGraw Hill: 2016. (accessible for free via Access Pharmacy online)
 
Other required resources